Caffeine-mediated changes of sex ratio in Chinese hamsters, Cricetulus griseus

J Reprod Fertil. 1975 Apr;43(1):141-3. doi: 10.1530/jrf.0.0430141.

Abstract

Sixty 6- to 10-week-old male Chinese hamsters were assigned to two groups. In one, the animals were untreated and in the other, they were treated with 0.02 g caffeine/100 ml water orally for 60 days. The sex ratio of the resulting litters showed a significant (P smaller than 0.025) skewing towards females (61.4%) when compared to that of the controls (49.2%).

MeSH terms

  • Administration, Oral
  • Animals
  • Caffeine / administration & dosage
  • Caffeine / pharmacology*
  • Cricetinae
  • Female
  • Humans
  • Male
  • Pregnancy
  • Sex Determination Analysis / drug effects*
  • Sex Ratio*

Substances

  • Caffeine